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Rater Training Services for CNS Clinical Trials

Sofpromed provides customized rater training services to maximize data quality, standardize assessments, and improve signal detection in central nervous system (CNS) clinical trials. Our experts are specialized in the main CNS clinical trial indications such as:
  • Mood disorders: bipolar disorder, major depressive disorder
  • Anxiety disorders: generalized anxiety disorder, posttraumatic stress disorder (PTSD), obsessive-compulsive disorder (OCD), social anxiety disorder
  • Psychotic disorders: schizophrenia, schizoaffective disorder
Our capabilities include:
  • CNS studies including centralized rating and training for psychedelic trials
  • Study-specific rater training/certification/calibration
  • Scale management/selection
  • Centralized/remote ratings
  • Study subject eligibility reviews
  • In-study data monitoring
  • In-study raters’ remediation/calibration
  • Electronic clinical outcome assessment (eCOA)
  • Video/audio recording of the assessments
Our team has experience in the following CNS rating scales:
    • Positive and Negative Syndrome Scale (PANSS)
    • Brief Psychiatric Rating Scale (BPRS)
    • Montgomery-Asberg Depression Scale (MADRS)
    • Hamilton Depression Rating Scale (HAM-D)
    • Hamilton Anxiety Rating Scale (HAM-A)
    • Young Mania Rating Scale (YMRS)
    • Clinical Global Impression Severity/Improvement (CGI-S/I)